- Animal Alliance of Canada
 - Nonprofit organization seeks to achieve long-term animal protection through public education and legislative advocacy. - Animal Rescue Coalition
- Provides temporary assistance to animals in need through food, shelter, and veterinary assistance, and finds them new homes.
- Atlantic Canadian Anti-Sealing Coalition
- Group working for the protection of seals across the Atlantic region by ending commercial seal hunting through peaceful and legal methods.
- Better Dog Network and Humane Society
- Pet rescue network and humane society.
- Brandon Humane Society
- A registered SPCA that assists, shelters, and re-homes companion animals, and educates the public on humane issues.
- Cambridge & District Humane Society - Ontario
- A nonprofit organization which survives on funds raised within the community it serves.
- Canadian Chihuahua Rescue & Transport
- Rescues, fosters, and provides necessary veterinary care for homeless, abandoned, neglected, abused, or unwanted Chihuahuas.
- Canadian Federation of Humane Societies
- The source for animal welfare information in Canada.
- Claws and Paws Rescue - Niagara Falls, Ontario
- No kill organization offering adoption and fostering opportunities.
- Fauna Foundation
- A sanctuary for retired biomedical research chimpanzees and neglected and abused farm and zoo animals. Also implements projects to increase awareness about environmental issues.
- Humane Society of Canada
- Protecting the rights of animals in Canada and around the world.
- Humane Society of Ottawa-Carleton
- Encourages responsible pet ownership and provides leadership in the humane treatment of all animals.
- Northern Alberta Society for Animal Protection
- A no-kill society that fosters animals until a permanent home can be found.
- Northern Ontario Animal Welfare Society
- Features bulletin board for pet postings in Northern Ontario, membership and donation information, pets available for adoption, and pet care tips.
- Owen Sound Animal Shelter
- Provides local pound information, animal care tips, lost and found pet form, and more.
- P.A.W.S.: People For Animal Welfare and Safety
- A volunteer organization providing interim care to animals in need until a new permanent home is found.
- Perth County Animal Shelter
- Operates on the principle that no one has the right to cause physical or mental pain and suffering to any animal.
- Scandinavian Anti-Sealing Coalition, The
- Organization aims to raise public awareness about cruelty involved in unnecessary seal hunting through legal and non-violent measures.
- Society for Animal Aid (Burlington) Inc.
- Nonprofit organization dedicated to saving stray and abandoned cats and dogs in the area.
- Society for the Prevention of Cruelty to Animals (7)
- Toronto Humane Society
- Promotes the humane care and protection of animals and handles lost, abandoned, unwanted, and injured pets and wildlife.
- Winnipeg Humane Society
- Features adopt-a-pet, tips, issues, news, and a kidz zone.
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